Dr Ankita S
MBBS, MS, DNB OBGY
What’s Endometrial cancer?
The onset of endometrial cancer occurs in the uterus. This type of cancer originates in the layer of cells that form the endometrium, or lining of the uterus, and is also known as uterine cancer. Although other forms of cancer, such as uterine sarcoma, can develop in the uterus, they are not as prevalent as endometrial cancer. Abnormal vaginal bleeding is a common symptom of endometrial cancer, and early detection is frequently possible. Surgical removal of the uterus is an effective treatment for endometrial cancer.
How does PCOS cause Endometrial Cancer
Understanding the relationship between these two conditions is essential for early diagnosis and treatment. PCOS patients have a higher risk of developing endometrial cancer than those without PCOS due to the build-up of unwanted uterus lining caused by irregular periods, which are common symptoms of PCOS. The common factor between PCOS and endometrial cancer is anovulation, which results in prolonged exposure of the endometrium to estrogen without sufficient progesterone. The complex interplay between PCOS and endometrial cancer has been extensively studied and has been found to have a direct impact on diabetes, obesity, hypertension, and anovulation. Women with PCOS have inherent differences in endometrial responsiveness to progesterone.
Treatment Regimens for PCOS Endometrial Hyperplasia Treatment
Abnormal vaginal bleeding caused by endometrial hyperplasia is typically linked to thickened and vulnerable endometrial tissue, which results from excessive estrogen activity without enough progesterone. To counteract the mitotic effects of estrogen on endometrial development, estrogen-progestin oral contraceptives can be used.
These progestogens promote the synchronized growth, development, and shedding of a structurally stable endometrium. If administered cyclically, progestogens should induce at least four episodes of withdrawal bleeding per year.
Women who are overweight should be advised to adopt lifestyle changes involving caloric restriction and exercise, in addition to medical treatment, to help reduce the risk of disease recurrence.
How to Prevent Endometrial Cancer with PCOS
- Handle menopause symptoms and sexual issues
- Lower your chances of getting infected
- Adjust your diet
- Engage in consistent physical activity
- Address fatigue
- Look for assistance
Conclusion
Therefore, the risk of developing endometrial cancer is 2.7 times higher in women with PCOS, with the majority of cases being well-differentiated tumors that have a positive prognosis. Women with PCOS who experience thickened endometrium, prolonged amenorrhea, unopposed estrogen exposure, or abnormal vaginal bleeding should undergo transvaginal ultrasound or endometrial biopsy as recommended and take the necessary treatment regimens as prescribed by their doctor.
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Our team of highly trained coaches and medical specialists at CysterCare are happy to answer any questions you may have and provide additional information so you can decide what is best for your individual needs.
Refernces
Frequently Asked Questions
Yes, women with PCOS have a higher risk of developing endometrial cancer due to irregular periods and the build-up of the uterine lining.
The common factor is anovulation, which leads to prolonged exposure of the endometrium to estrogen without sufficient progesterone, increasing the risk of endometrial cancer.
Treatment options may include estrogen-progestin oral contraceptives, lifestyle changes (diet and exercise), and medical treatment to reduce the risk of disease recurrence.
Lifestyle adjustments like quitting smoking, maintaining a healthy diet, engaging in regular physical activity, and seeking medical assistance can help reduce the risk.
PCOS patients experiencing thickened endometrium, prolonged amenorrhea, abnormal bleeding, or other concerning symptoms should undergo regular screenings like transvaginal ultrasound or endometrial biopsy as recommended by their doctor.
Dr Ankita S
MBBS, MS, DNB OBGY
M.Tech Food Biotechnologist
M.Tech Food Biotechnologist
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